Cargando…

Synthesis, α-glucosidase inhibition, α-amylase inhibition, and molecular docking studies of 3,3-di(indolyl)indolin-2-ones

The synthesized 3,3-di(indolyl)indolin-2-ones 1a-p showed desired higher α-glucosidase inhibitory activities and lower α-amylase inhibitory activities than standard drug acarbose. Particularly, compound 1i showed favorable higher α-glucosidase % inhibition of 67 ± 13 and lower α-amylase % inhibition...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santoso, Mardi, Ong, Li Lin, Aijijiyah, Nur Pasca, Wati, First Ambar, Azminah, Azminah, Annuur, Rose Malina, Fadlan, Arif, Judeh, Zaher M.A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917276/ https://www.ncbi.nlm.nih.gov/pubmed/35287328 http://dx.doi.org/10.1016/j.heliyon.2022.e09045

Ejemplares similares

Chemistry of trisindolines: natural occurrence, synthesis and bioactivity
por: Wati, First Ambar, et al.
Publicado: (2021)

Inhibition of α-glucosidase, α-amylase, and aldose reductase by potato polyphenolic compounds
por: Kalita, Diganta, et al.
Publicado: (2018)

The α-Amylase and α-Glucosidase Inhibition Capacity of Grape Pomace: A Review
por: Cisneros-Yupanqui, Miluska, et al.
Publicado: (2022)

A Review of the In Vitro Inhibition of α-Amylase and α-Glucosidase by Chalcone Derivatives
por: Tran, Thanh-Dao, et al.
Publicado: (2023)

A Concise Synthesis of Pyrrole-Based Drug Candidates from α-Hydroxyketones, 3-Oxobutanenitrile, and Anilines
por: Xia, Mengxin, et al.
Publicado: (2023)

Modes of Inhibition of α-Amylase and α-Glucosidase by Aqueous Extract of Morinda lucida Benth Leaf
por: Kazeem, M. I., et al.
Publicado: (2013)

In Vitro Inhibition of α-Amylase and α-Glucosidase by Extracts from Psiadia punctulata and Meriandra bengalensis
por: Kidane, Yosief, et al.
Publicado: (2018)

Effect of storage time on antioxidant activity and inhibition on α‐Amylase and α‐Glucosidase of white tea
por: Xu, Ping, et al.
Publicado: (2019)

Phytochemical Screening, Antioxidant, and Inhibition Activity of Picrorhiza kurroa Against α-Amylase and α-Glucosidase
por: Nisar, Jaweria, et al.
Publicado: (2022)

Antidiabetic potential of Asparagus racemosus Willd leaf extracts through inhibition of α-amylase and α-glucosidase
por: Vadivelan, R., et al.
Publicado: (2018)

Inhibition Kinetics and Theoretical Studies on Zanthoxylum chalybeum Engl. Dual Inhibitors of α-Glucosidase and α-Amylase
por: Kimani, Njogu M., et al.
Publicado: (2023)

Molecular Modeling and Synthesis of Indoline-2,3-dione-Based Benzene Sulfonamide Derivatives and Their Inhibitory Activity against α-Glucosidase and α-Amylase Enzymes
por: Rasheed, Liaqat, et al.
Publicado: (2023)

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase
por: Ćorković, Ina, et al.
Publicado: (2022)

Inhibition of α-Amylase, α-Glucosidase, and Lipase, Intestinal Glucose Absorption, and Antidiabetic Properties by Extracts of Erodium guttatum
por: Benrahou, Kaoutar, et al.
Publicado: (2022)

In Vitro α-Amylase, α-Glucosidase, Pancreatic Lipase, Xanthine Oxidase Inhibiting Activity of Agaricus bisporus Extracts
por: Kim, Jung Han, et al.
Publicado: (2023)

The ingredients in Saengshik, a formulated health food, inhibited the activity of α-amylase and α-glucosidase as anti-diabetic function
por: Kim, Misook, et al.
Publicado: (2014)

Structural elucidation, molecular docking, α-amylase and α-glucosidase inhibition studies of 5-amino-nicotinic acid derivatives
por: Nawaz, Muhammad, et al.
Publicado: (2020)

Inhibition Effect of Extract of Psychotria viridiflora Stem on α-Amylase and α-Glucosidase and Its Application in Lowering the Digestibility of Noodles
por: Chen, Qimin, et al.
Publicado: (2021)

Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and α-amylase and α-glucosidase activity
por: Floris, Sonia, et al.
Publicado: (2021)

Immobilization of Chondroitin Sulfate A onto Monolithic Epoxy Silica Column as a New Chiral Stationary Phase for High-Performance Liquid Chromatographic Enantioseparation
por: Ratih, Ratih, et al.
Publicado: (2021)

Optimization of betaine-sorbitol natural deep eutectic solvent-based ultrasound-assisted extraction and pancreatic lipase inhibitory activity of chlorogenic acid and caffeine content from robusta green coffee beans
por: Ahmad, Islamudin, et al.
Publicado: (2021)

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase
por: Sansenya, Sompong, et al.
Publicado: (2020)

Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose
por: Oboh, Ganiyu, et al.
Publicado: (2016)

Smilax aristolochiifolia Root Extract and Its Compounds Chlorogenic Acid and Astilbin Inhibit the Activity of α-Amylase and α-Glucosidase Enzymes
por: Pérez-Nájera, Viridiana Candelaria, et al.
Publicado: (2018)

Multimodal α-Glucosidase and α-Amylase Inhibition and Antioxidant Effect of the Aqueous and Methanol Extracts from the Trunk Bark of Ceiba pentandra
por: Nguelefack, Telesphore Benoit, et al.
Publicado: (2020)

Inhibition of α-Amylase and α-Glucosidase of Anthocyanin Isolated from Berberis integerrima Bunge Fruits: A Model of Antidiabetic Compounds
por: Moein, Soheila, et al.
Publicado: (2022)

Isolated compounds from Dracaena angustifolia Roxb and acarbose synergistically/additively inhibit α-glucosidase and α-amylase: an in vitro study
por: Yi, Jiling, et al.
Publicado: (2022)

Efficacy of Rytigynia senegalensis Blume on Free Radical Scavenging, Inhibition of α-Amylase and α-Glucosidase Activity, and Blood Glucose Level
por: Maidadi, Barthelemy, et al.
Publicado: (2022)

Hypoglycemic Efficacy of Docking Selected Natural Compounds against α-Glucosidase and α-Amylase
por: Riyaphan, Jirawat, et al.
Publicado: (2018)

Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase
por: Altowyan, Mezna Saleh, et al.
Publicado: (2019)

α-Glucosidase, α-Amylase and Antioxidant Evaluations of Isolated Bioactives from Wild Strawberry
por: Huneif, Mohammed A., et al.
Publicado: (2022)

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors
por: Ke, Jun-Jie, et al.
Publicado: (2022)

Effect of Black Tea and Black Tea Pomace Polyphenols on α-Glucosidase and α-Amylase Inhibition, Relevant to Type 2 Diabetes Prevention
por: Striegel, Lisa, et al.
Publicado: (2015)

Bioactive Peptides from Germinated Soybean with Anti-Diabetic Potential by Inhibition of Dipeptidyl Peptidase-IV, α-Amylase, and α-Glucosidase Enzymes
por: González-Montoya, Marcela, et al.
Publicado: (2018)

Standardized Emblica officinalis fruit extract inhibited the activities of α‐amylase, α‐glucosidase, and dipeptidyl peptidase‐4 and displayed antioxidant potential
por: Majeed, Muhammed, et al.
Publicado: (2019)

Ephedra alata fruit extracts: phytochemical screening, anti-proliferative activity and inhibition of DPPH, α-amylase, α-glucosidase, and lipase enzymes
por: Jaradat, Nidal, et al.
Publicado: (2021)

Probiotic Potential Lacticaseibacillus casei and Limosilactobacillus fermentum Strains Isolated from Dosa Batter Inhibit α-Glucosidase and α-Amylase Enzymes
por: Kumari V. B., Chandana, et al.
Publicado: (2022)

Effects of topping on rhizome, and analysis of chemical composition, antioxidant activity and α-amylase and α-glucosidase inhibition of the aerial parts in Polygonatum cyrtonema
por: Tang, Wenwen, et al.
Publicado: (2023)

In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract
por: Ganeshpurkar, Aditya, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8md9pvpkub4upro52popp7ttue