ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma

BACKGROUND: Tumor vessels in glioma are molecularly and functionally abnormal, contributing to treatment resistance. Proteins differentially expressed in glioma vessels can change vessel phenotype and be targeted for therapy. ELTD1 (Adgrl4) is an orphan member of the adhesion G-protein-coupled recep...

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Detalles Bibliográficos
Autores principales: Huang, Hua, Georganaki, Maria, Conze, Lei Liu, Laviña, Bàrbara, van Hooren, Luuk, Vemuri, Kalyani, van de Walle, Tiarne, Ramachandran, Mohanraj, Zhang, Lei, Pontén, Fredrik, Bergqvist, Michael, Smits, Anja, Betsholtz, Christer, Dejana, Elisabetta, Magnusson, Peetra U, He, Liqun, Lugano, Roberta, Dimberg, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917395/
https://www.ncbi.nlm.nih.gov/pubmed/34347079
http://dx.doi.org/10.1093/neuonc/noab181

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