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Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage

The canonical Wnt/β-catenin pathway governs a multitude of developmental processes in various cell lineages, including the melanocyte lineage. Indeed, β-catenin regulates transcription of Mitf-M, the master regulator of this lineage. The first wave of melanocytes to colonize the skin is directly der...

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Detalles Bibliográficos
Autores principales: Colombo, Sophie, Petit, Valérie, Wagner, Roselyne Y., Champeval, Delphine, Yajima, Ichiro, Gesbert, Franck, Aktary, Zackie, Davidson, Irwin, Delmas, Véronique, Larue, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917410/
https://www.ncbi.nlm.nih.gov/pubmed/34878101
http://dx.doi.org/10.1242/dev.194407