Liver injury in COVID-19: pathological findings

Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms i...

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Detalles Bibliográficos
Autores principales: Zghal, Mouna, Bouhamed, Marwa, Mellouli, Manel, Triki, Meriam, Kallel, Rim, Ayedi, Lobna, Boudawara, Tahya Sellami, Makni, Saadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917459/
https://www.ncbi.nlm.nih.gov/pubmed/35317475
http://dx.doi.org/10.11604/pamj.2022.41.56.31114
Descripción
Sumario:Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms involved in liver injury in Coronavirus disease 2019 infection are not yet established. In this paper, we summarize the spectrum of pathologic findings of liver injury in patients infected by SARS-CoV-2 and we discuss the clinicopathological correlation and the mechanisms of liver damage in Coronavirus disease 2019 infection.

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