Liver injury in COVID-19: pathological findings

Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms i...

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Autores principales: Zghal, Mouna, Bouhamed, Marwa, Mellouli, Manel, Triki, Meriam, Kallel, Rim, Ayedi, Lobna, Boudawara, Tahya Sellami, Makni, Saadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917459/
https://www.ncbi.nlm.nih.gov/pubmed/35317475
http://dx.doi.org/10.11604/pamj.2022.41.56.31114
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author Zghal, Mouna
Bouhamed, Marwa
Mellouli, Manel
Triki, Meriam
Kallel, Rim
Ayedi, Lobna
Boudawara, Tahya Sellami
Makni, Saadia
author_facet Zghal, Mouna
Bouhamed, Marwa
Mellouli, Manel
Triki, Meriam
Kallel, Rim
Ayedi, Lobna
Boudawara, Tahya Sellami
Makni, Saadia
author_sort Zghal, Mouna
collection PubMed
description Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms involved in liver injury in Coronavirus disease 2019 infection are not yet established. In this paper, we summarize the spectrum of pathologic findings of liver injury in patients infected by SARS-CoV-2 and we discuss the clinicopathological correlation and the mechanisms of liver damage in Coronavirus disease 2019 infection.
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spelling pubmed-89174592022-03-21 Liver injury in COVID-19: pathological findings Zghal, Mouna Bouhamed, Marwa Mellouli, Manel Triki, Meriam Kallel, Rim Ayedi, Lobna Boudawara, Tahya Sellami Makni, Saadia Pan Afr Med J Commentary Hepatic injuries have been reported in patients with Coronavirus disease 2019 infection, particularly in those with moderate to severe illness. To date, pathological changes caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in liver tissue are unclear. Moreover, the mechanisms involved in liver injury in Coronavirus disease 2019 infection are not yet established. In this paper, we summarize the spectrum of pathologic findings of liver injury in patients infected by SARS-CoV-2 and we discuss the clinicopathological correlation and the mechanisms of liver damage in Coronavirus disease 2019 infection. The African Field Epidemiology Network 2022-01-20 /pmc/articles/PMC8917459/ /pubmed/35317475 http://dx.doi.org/10.11604/pamj.2022.41.56.31114 Text en Copyright: Mouna Zghal et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Zghal, Mouna
Bouhamed, Marwa
Mellouli, Manel
Triki, Meriam
Kallel, Rim
Ayedi, Lobna
Boudawara, Tahya Sellami
Makni, Saadia
Liver injury in COVID-19: pathological findings
title Liver injury in COVID-19: pathological findings
title_full Liver injury in COVID-19: pathological findings
title_fullStr Liver injury in COVID-19: pathological findings
title_full_unstemmed Liver injury in COVID-19: pathological findings
title_short Liver injury in COVID-19: pathological findings
title_sort liver injury in covid-19: pathological findings
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917459/
https://www.ncbi.nlm.nih.gov/pubmed/35317475
http://dx.doi.org/10.11604/pamj.2022.41.56.31114
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