Cargando…

Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases

We report two consecutive cases of toxic epidermal necrolysis presented to our emergency department in the past 5 months. Both patients had history of fever prior to the onset of skin manifestations and showed radiological findings suggestive of COVID-19 pneumonia and elevated D dimers. ALDEN score...

Descripción completa

Detalles Bibliográficos
Autores principales: Aulakh, Shayna, Arora, Raina, Sarangal, Rishu, Chopra, Dimple
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917493/
https://www.ncbi.nlm.nih.gov/pubmed/35287406
http://dx.doi.org/10.4103/idoj.idoj_510_21
_version_ 1784668558382333952
author Aulakh, Shayna
Arora, Raina
Sarangal, Rishu
Chopra, Dimple
author_facet Aulakh, Shayna
Arora, Raina
Sarangal, Rishu
Chopra, Dimple
author_sort Aulakh, Shayna
collection PubMed
description We report two consecutive cases of toxic epidermal necrolysis presented to our emergency department in the past 5 months. Both patients had history of fever prior to the onset of skin manifestations and showed radiological findings suggestive of COVID-19 pneumonia and elevated D dimers. ALDEN score was used to assess the drug causality, which showed probable and possible associations, respectively. In this report, along with brief review of literature, we highlight the possible role of viral etiology, that is SARS-Cov2, in triggering toxic epidermal necrolysis.
format Online
Article
Text
id pubmed-8917493
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-89174932022-03-13 Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases Aulakh, Shayna Arora, Raina Sarangal, Rishu Chopra, Dimple Indian Dermatol Online J Case Report We report two consecutive cases of toxic epidermal necrolysis presented to our emergency department in the past 5 months. Both patients had history of fever prior to the onset of skin manifestations and showed radiological findings suggestive of COVID-19 pneumonia and elevated D dimers. ALDEN score was used to assess the drug causality, which showed probable and possible associations, respectively. In this report, along with brief review of literature, we highlight the possible role of viral etiology, that is SARS-Cov2, in triggering toxic epidermal necrolysis. Wolters Kluwer - Medknow 2022-03-03 /pmc/articles/PMC8917493/ /pubmed/35287406 http://dx.doi.org/10.4103/idoj.idoj_510_21 Text en Copyright: © 2022 Indian Dermatology Online Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Aulakh, Shayna
Arora, Raina
Sarangal, Rishu
Chopra, Dimple
Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases
title Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases
title_full Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases
title_fullStr Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases
title_full_unstemmed Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases
title_short Increased Predisposition of SJS TEN in COVID-19 Patients, Presenting as Post COVID Complication: Report of Two Cases
title_sort increased predisposition of sjs ten in covid-19 patients, presenting as post covid complication: report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917493/
https://www.ncbi.nlm.nih.gov/pubmed/35287406
http://dx.doi.org/10.4103/idoj.idoj_510_21
work_keys_str_mv AT aulakhshayna increasedpredispositionofsjstenincovid19patientspresentingaspostcovidcomplicationreportoftwocases
AT aroraraina increasedpredispositionofsjstenincovid19patientspresentingaspostcovidcomplicationreportoftwocases
AT sarangalrishu increasedpredispositionofsjstenincovid19patientspresentingaspostcovidcomplicationreportoftwocases
AT chopradimple increasedpredispositionofsjstenincovid19patientspresentingaspostcovidcomplicationreportoftwocases