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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis

Receptor interacting protein kinase 1 (RIPK1) mediates cell death and inflammatory signaling and is increased in multiple sclerosis (MS) brain samples. Here, we investigate the role of glial RIPK1 kinase activity in mediating MS pathogenesis. We demonstrate RIPK1 levels correlate with MS disease pro...

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Detalles Bibliográficos
Autores principales:	Zelic, Matija, Pontarelli, Fabrizio, Woodworth, Lisa, Zhu, Cheng, Mahan, Amy, Ren, Yi, LaMorte, Michael, Gruber, Ross, Keane, Aislinn, Loring, Pequita, Guo, Lilu, Xia, Tai-he, Zhang, Boyao, Orning, Pontus, Lien, Egil, Degterev, Alexei, Hammond, Timothy, Ofengeim, Dimitry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917516/ https://www.ncbi.nlm.nih.gov/pubmed/33979622 http://dx.doi.org/10.1016/j.celrep.2021.109112

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