Harada-like syndrome post-Covishield vaccination: A rare adverse effect

Covishield is in wide use in India with about 80% efficacy. Serious side effects are still under study. A 30-year-old female presented to us 7 days post-vaccination with a 5-day history of sudden diminution of vision in both eyes. The clinical findings were suggestive of the Vogt-Koyanagi-Harada (VK...

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Autores principales: Reddy, Yogya, Pandey, Anamika, Ojha, Ayushi, Ramchandani, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Expedited Publications, Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917518/
https://www.ncbi.nlm.nih.gov/pubmed/34937269
http://dx.doi.org/10.4103/ijo.IJO_2589_21
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author Reddy, Yogya
Pandey, Anamika
Ojha, Ayushi
Ramchandani, Suresh
author_facet Reddy, Yogya
Pandey, Anamika
Ojha, Ayushi
Ramchandani, Suresh
author_sort Reddy, Yogya
collection PubMed
description Covishield is in wide use in India with about 80% efficacy. Serious side effects are still under study. A 30-year-old female presented to us 7 days post-vaccination with a 5-day history of sudden diminution of vision in both eyes. The clinical findings were suggestive of the Vogt-Koyanagi-Harada (VKH) syndrome. She was treated with high-dose oral steroids. At this juncture, the association was unclear. However, it was justified by an acute flare-up of uveitis on day 2 post the second dose of vaccination despite ongoing steroids. A direct correlation of Harada-like syndrome with the Covishield vaccine is observed here.
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spelling pubmed-89175182022-03-13 Harada-like syndrome post-Covishield vaccination: A rare adverse effect Reddy, Yogya Pandey, Anamika Ojha, Ayushi Ramchandani, Suresh Indian J Ophthalmol Expedited Publications, Case Reports Covishield is in wide use in India with about 80% efficacy. Serious side effects are still under study. A 30-year-old female presented to us 7 days post-vaccination with a 5-day history of sudden diminution of vision in both eyes. The clinical findings were suggestive of the Vogt-Koyanagi-Harada (VKH) syndrome. She was treated with high-dose oral steroids. At this juncture, the association was unclear. However, it was justified by an acute flare-up of uveitis on day 2 post the second dose of vaccination despite ongoing steroids. A direct correlation of Harada-like syndrome with the Covishield vaccine is observed here. Wolters Kluwer - Medknow 2022-01 2021-12-23 /pmc/articles/PMC8917518/ /pubmed/34937269 http://dx.doi.org/10.4103/ijo.IJO_2589_21 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Expedited Publications, Case Reports
Reddy, Yogya
Pandey, Anamika
Ojha, Ayushi
Ramchandani, Suresh
Harada-like syndrome post-Covishield vaccination: A rare adverse effect
title Harada-like syndrome post-Covishield vaccination: A rare adverse effect
title_full Harada-like syndrome post-Covishield vaccination: A rare adverse effect
title_fullStr Harada-like syndrome post-Covishield vaccination: A rare adverse effect
title_full_unstemmed Harada-like syndrome post-Covishield vaccination: A rare adverse effect
title_short Harada-like syndrome post-Covishield vaccination: A rare adverse effect
title_sort harada-like syndrome post-covishield vaccination: a rare adverse effect
topic Expedited Publications, Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917518/
https://www.ncbi.nlm.nih.gov/pubmed/34937269
http://dx.doi.org/10.4103/ijo.IJO_2589_21
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AT ojhaayushi haradalikesyndromepostcovishieldvaccinationarareadverseeffect
AT ramchandanisuresh haradalikesyndromepostcovishieldvaccinationarareadverseeffect

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