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Ageing attenuates bone healing by mesenchymal stem cells in a microribbon hydrogel with a murine long bone critical-size defect model

BACKGROUND: Despite the high incidence of fractures and pseudoarthrosis in the aged population, a potential role for the use of mesenchymal stem cells (MSCs) in the treatment of bone defects in elderly patients has not been elucidated. Inflammation and the innate immune system, including macrophages...

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Detalles Bibliográficos
Autores principales: Hirata, Hirohito, Zhang, Ning, Ueno, Masaya, Barati, Danial, Kushioka, Junichi, Shen, Huaishuang, Tsubosaka, Masanori, Toya, Masakazu, Lin, Tzuhua, Huang, Ejun, Yao, Zhenyu, Wu, Joy Y., Zwingenberger, Stefan, Yang, Fan, Goodman, Stuart B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917642/
https://www.ncbi.nlm.nih.gov/pubmed/35279175
http://dx.doi.org/10.1186/s12979-022-00272-1