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Chromatin accessibility and transcriptome integrative analysis revealed AP-1-mediated genes potentially modulate histopathology features in psoriasis

BACKGROUND: Psoriasis is a chronic and hyperproliferative skin disease featured by hyperkeratosis with parakeratosis, Munro micro-abscess, elongation of rete pegs, granulosa thinning, and lymphocyte infiltration. We previously profiled gene expression and chromatin accessibility of psoriatic skins b...

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Detalles Bibliográficos
Autores principales:	Xu, Xiaoqing, Tang, Xianfa, Zhang, Yuxi, Pan, Zhaobing, Wang, Qingping, Tang, Lili, Zhu, Caihong, Cheng, Hui, Zhou, Fusheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917665/ https://www.ncbi.nlm.nih.gov/pubmed/35277199 http://dx.doi.org/10.1186/s13148-022-01250-6

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