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Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is a process linked to metastasis and drug resistance with non-coding RNAs (ncRNAs) playing pivotal roles. We previously showed that miR-100 and miR-125b, embedded within the third intron of the ncRNA host gene MIR100HG, confer resistance to cet...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Li, Danxiu, Sun, Lina, Qin, Hongqiang, Fan, Ahui, Meng, Lingnan, Graves-Deal, Ramona, Glass, Sarah E., Franklin, Jeffrey L., Liu, Qi, Wang, Jing, Yeatman, Timothy J., Guo, Hao, Zong, Hong, Jin, Shuilin, Chen, Zhiyu, Deng, Ting, Fang, Ying, Li, Cunxi, Karijolich, John, Patton, James G., Wang, Xin, Nie, Yongzhan, Fan, Daiming, Coffey, Robert J., Zhao, Xiaodi, Lu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917698/
https://www.ncbi.nlm.nih.gov/pubmed/35279145
http://dx.doi.org/10.1186/s12943-022-01555-3