Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth

BACKGROUND: Mitochondrial fusion and fission proteins have been nominated as druggable targets in cancer. Whether their inhibition is efficacious in triple negative breast cancer (TNBC) that almost invariably develops chemoresistance is unknown. METHODS: We used a combination of bioinformatics analy...

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Detalles Bibliográficos
Autores principales: Zamberlan, Margherita, Boeckx, Amandine, Muller, Florian, Vinelli, Federica, Ek, Olivier, Vianello, Caterina, Coart, Emeline, Shibata, Keitaro, Christian, Aurélie, Grespi, Francesca, Giacomello, Marta, Struman, Ingrid, Scorrano, Luca, Herkenne, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917763/
https://www.ncbi.nlm.nih.gov/pubmed/35279198
http://dx.doi.org/10.1186/s13046-022-02304-6

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