Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses

BACKGROUND: Circulating tumor cells (CTCs) are liquid biopsies that represent micrometastatic disease and may offer unique insights into future recurrences in non-small cell lung cancer (NSCLC). Due to CTC rarity and limited stability, no stable CTC-derived xenograft (CDX) models have ever been gene...

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Detalles Bibliográficos
Autores principales: Suvilesh, Kanve N., Nussbaum, Yulia I., Radhakrishnan, Vijay, Manjunath, Yariswamy, Avella, Diego M., Staveley-O’Carroll, Kevin F., Kimchi, Eric T., Chaudhuri, Aadel A., Shyu, Chi-Ren, Li, Guangfu, Pantel, Klaus, Warren, Wesley C., Mitchem, Jonathan B., Kaifi, Jussuf T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917773/
https://www.ncbi.nlm.nih.gov/pubmed/35279152
http://dx.doi.org/10.1186/s12943-022-01553-5

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