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SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet

Prolonged high-fat diet (HFD) accelerates the cardiovascular, renal, and metabolic dysfunction in hypertensive rats with altered renal development (ARDev). Soluble guanylate cyclase (sGC) stimulation or sodium-glucose cotransporter 2 (SGLT2) inhibition may improve cardiovascular, renal, and metaboli...

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Detalles Bibliográficos
Autores principales:	Reverte, Virginia, Rodriguez, Francisca, Oltra, Lidia, Moreno, Juan M., Llinás, María T., Shea, Courtney M., Schwartzkopf, Chad D., Buys, Emmanuel S., Masferrer, Jaime L., Salazar, F. Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917931/ https://www.ncbi.nlm.nih.gov/pubmed/35119333 http://dx.doi.org/10.1152/ajpheart.00386.2021

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