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A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern

BACKGROUND: Current SARS-CoV-2 detection platforms lack the ability to differentiate among variants of concern (VOCs) in an efficient manner. CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated) based detection systems have the potential to transform the landscape...

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Detalles Bibliográficos
Autores principales:	Nguyen, Long T., Macaluso, Nicolas C., Pizzano, Brianna L.M., Cash, Melanie N., Spacek, Jan, Karasek, Jan, Miller, Megan R., Lednicky, John A., Dinglasan, Rhoel R., Salemi, Marco, Jain, Piyush K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917962/ https://www.ncbi.nlm.nih.gov/pubmed/35290826 http://dx.doi.org/10.1016/j.ebiom.2022.103926

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