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Pixel-CO(2) laser for the treatment of stress urinary incontinence

ABSTRACT: The aim of this study was to assess the safety and efficacy of a minimally invasive pixel-CO(2) laser procedure for the treatment of stress urinary incontinence (SUI). This was a prospective, open-label study with a cohort of 59 women. Patients were treated intravaginally with a fractional...

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Autores principales: Nalewczynska, Agnieszka Aleksandra, Barwijuk, Michael, Kolczewski, Piotr, Dmoch-Gajzlerska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918174/
https://www.ncbi.nlm.nih.gov/pubmed/34382127
http://dx.doi.org/10.1007/s10103-021-03353-7
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author Nalewczynska, Agnieszka Aleksandra
Barwijuk, Michael
Kolczewski, Piotr
Dmoch-Gajzlerska, Ewa
author_facet Nalewczynska, Agnieszka Aleksandra
Barwijuk, Michael
Kolczewski, Piotr
Dmoch-Gajzlerska, Ewa
author_sort Nalewczynska, Agnieszka Aleksandra
collection PubMed
description ABSTRACT: The aim of this study was to assess the safety and efficacy of a minimally invasive pixel-CO(2) laser procedure for the treatment of stress urinary incontinence (SUI). This was a prospective, open-label study with a cohort of 59 women. Patients were treated intravaginally with a fractional/pixel CO(2) laser every 4–6 weeks for a total of three treatments and assessed at 3, 6, and 12 months. Evaluation tools included a Sandvik severity score based on a validated questionnaire, 1-h pad test, vaginal health index score (VHIS), validated female sexual function index (FSFI), patient’s impression of disease severity (PGI-S), global impression of improvement (PGI-I), and the short-term pelvic floor impact questionnaire (PFIQ-7) to assess improvements in quality of life. Reduction in SUI severity was noticed throughout the duration of the study, as compared to the baseline in which 2% of the patients were defined as “slight,” 73% “moderate,” and 25% “severe.” Gradual improvement of symptoms resulted in redistribution of severity score and the best outcome observed between 3 and 6 months. Sanitary pad weight declined from an average of 35.45 g per day at baseline to 12.47 g at the 3rd treatment, and increased to 23.06 g at 12 months. Vaginal acidity changes showed a similar pattern. No serious adverse events were reported. Pixel-CO(2) laser is safe and effective for treating SUI. Additional maintenance treatments should be considered during the 6–12-month post-treatment period in order to maintain the beneficial effects. BRIEF SUMMARY: Pixel-CO(2) laser is a safe and effective treatment for SUI. Maintenance treatments should be considered at 6–12 months.
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spelling pubmed-89181742022-03-17 Pixel-CO(2) laser for the treatment of stress urinary incontinence Nalewczynska, Agnieszka Aleksandra Barwijuk, Michael Kolczewski, Piotr Dmoch-Gajzlerska, Ewa Lasers Med Sci Original Article ABSTRACT: The aim of this study was to assess the safety and efficacy of a minimally invasive pixel-CO(2) laser procedure for the treatment of stress urinary incontinence (SUI). This was a prospective, open-label study with a cohort of 59 women. Patients were treated intravaginally with a fractional/pixel CO(2) laser every 4–6 weeks for a total of three treatments and assessed at 3, 6, and 12 months. Evaluation tools included a Sandvik severity score based on a validated questionnaire, 1-h pad test, vaginal health index score (VHIS), validated female sexual function index (FSFI), patient’s impression of disease severity (PGI-S), global impression of improvement (PGI-I), and the short-term pelvic floor impact questionnaire (PFIQ-7) to assess improvements in quality of life. Reduction in SUI severity was noticed throughout the duration of the study, as compared to the baseline in which 2% of the patients were defined as “slight,” 73% “moderate,” and 25% “severe.” Gradual improvement of symptoms resulted in redistribution of severity score and the best outcome observed between 3 and 6 months. Sanitary pad weight declined from an average of 35.45 g per day at baseline to 12.47 g at the 3rd treatment, and increased to 23.06 g at 12 months. Vaginal acidity changes showed a similar pattern. No serious adverse events were reported. Pixel-CO(2) laser is safe and effective for treating SUI. Additional maintenance treatments should be considered during the 6–12-month post-treatment period in order to maintain the beneficial effects. BRIEF SUMMARY: Pixel-CO(2) laser is a safe and effective treatment for SUI. Maintenance treatments should be considered at 6–12 months. Springer London 2021-08-12 2022 /pmc/articles/PMC8918174/ /pubmed/34382127 http://dx.doi.org/10.1007/s10103-021-03353-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Nalewczynska, Agnieszka Aleksandra
Barwijuk, Michael
Kolczewski, Piotr
Dmoch-Gajzlerska, Ewa
Pixel-CO(2) laser for the treatment of stress urinary incontinence
title Pixel-CO(2) laser for the treatment of stress urinary incontinence
title_full Pixel-CO(2) laser for the treatment of stress urinary incontinence
title_fullStr Pixel-CO(2) laser for the treatment of stress urinary incontinence
title_full_unstemmed Pixel-CO(2) laser for the treatment of stress urinary incontinence
title_short Pixel-CO(2) laser for the treatment of stress urinary incontinence
title_sort pixel-co(2) laser for the treatment of stress urinary incontinence
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918174/
https://www.ncbi.nlm.nih.gov/pubmed/34382127
http://dx.doi.org/10.1007/s10103-021-03353-7
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