Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies

OBJECTIVE: Maternal glycemic dysregulation during pregnancy increases the risk of adverse health outcomes in her offspring, a risk thought to be linearly related to maternal hyperglycemia. It is hypothesized that changes in offspring DNA methylation (DNAm) underline these associations. RESEARCH DESI...

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Detalles Bibliográficos
Autores principales: Tobi, Elmar W., Juvinao-Quintero, Diana L., Ronkainen, Justiina, Ott, Raffael, Alfano, Rossella, Canouil, Mickaël, Geurtsen, Madelon L., Khamis, Amna, Küpers, Leanne K., Lim, Ives Y., Perron, Patrice, Pesce, Giancarlo, Tuhkanen, Johanna, Starling, Anne P., Andrew, Toby, Binder, Elisabeth, Caiazzo, Robert, Chan, Jerry K.Y., Gaillard, Romy, Gluckman, Peter D., Keikkala, Elina, Karnani, Neerja, Mustaniemi, Sanna, Nawrot, Tim S., Pattou, François, Plusquin, Michelle, Raverdy, Violeta, Tan, Kok Hian, Tzala, Evangelia, Raikkonen, Katri, Winkler, Christiane, Ziegler, Anette-G., Annesi-Maesano, Isabella, Bouchard, Luigi, Chong, Yap Seng, Dabelea, Dana, Felix, Janine F., Heude, Barbara, Jaddoe, Vincent W.V., Lahti, Jari, Reimann, Brigitte, Vääräsmäki, Marja, Bonnefond, Amélie, Froguel, Philippe, Hummel, Sandra, Kajantie, Eero, Jarvelin, Marjo-Riita, Steegers-Theunissen, Regine P.M., Howe, Caitlin G., Hivert, Marie-France, Sebert, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Epidemiology/Health Services Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918264/
https://www.ncbi.nlm.nih.gov/pubmed/35104326
http://dx.doi.org/10.2337/dc21-1701

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