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Blocking GSDME-mediated pyroptosis in renal tubular epithelial cells alleviates disease activity in lupus mice

An increase in apoptosis and/or defects in the clearance of apoptotic cells resulting in massive secondary necrosis have been recognized as the main causes of systemic lupus erythematosus (SLE). Recent findings have revealed that gasdermin E (GSDME)-mediated pyroptosis is a mechanism associated with...

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Detalles Bibliográficos
Autores principales:	Luo, Guihu, He, Yi, Yang, Fangyuan, Zhai, Zeqing, Han, Jiaochan, Xu, Wenchao, Zhang, Jialin, Zhuang, Lili, Zhang, Yanan, Li, Yehao, Song, Rui, Luo, Xiaoqing, Liang, Jianheng, Sun, Erwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918340/ https://www.ncbi.nlm.nih.gov/pubmed/35279675 http://dx.doi.org/10.1038/s41420-022-00848-2

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