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Precision dentistry—what it is, where it fails (yet), and how to get there

OBJECTIVES: Dentistry is stuck between the one-size-fits-all approach towards diagnostics and therapy employed for a century and the era of stratified medicine. The present review presents the concept of precision dentistry, i.e., the next step beyond stratification into risk groups, and lays out wh...

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Autores principales: Schwendicke, Falk, Krois, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918420/
https://www.ncbi.nlm.nih.gov/pubmed/35284954
http://dx.doi.org/10.1007/s00784-022-04420-1
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author Schwendicke, Falk
Krois, Joachim
author_facet Schwendicke, Falk
Krois, Joachim
author_sort Schwendicke, Falk
collection PubMed
description OBJECTIVES: Dentistry is stuck between the one-size-fits-all approach towards diagnostics and therapy employed for a century and the era of stratified medicine. The present review presents the concept of precision dentistry, i.e., the next step beyond stratification into risk groups, and lays out where we stand, but also what challenges we have ahead for precision dentistry to come true. MATERIAL AND METHODS: Narrative literature review. RESULTS: Current approaches for enabling more precise diagnostics and therapies focus on stratification of individuals using clinical or social risk factors or indicators. Most research in dentistry does not focus on predictions — the key for precision dentistry — but on associations. We critically discuss why both approaches (focus on a limited number of risk factors or indicators and on associations) are insufficient and elaborate on what we think may allow to overcome the status quo. CONCLUSIONS: Leveraging more diverse and broad data stemming from routine or unusual sources via advanced data analytics and testing the resulting prediction models rigorously may allow further steps towards more precise oral and dental care. CLINICAL SIGNIFICANCE: Precision dentistry refers to tailoring diagnostics and therapy to an individual; it builds on modelling, prediction making and rigorous testing. Most studies in the dental domain focus on showing associations, and do not attempt to make any predictions. Moreover, the datasets used are narrow and usually collected purposively following a clinical reasoning. Opening routine data silos and involving uncommon data sources to harvest broad data and leverage them using advanced analytics could facilitate precision dentistry.
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spelling pubmed-89184202022-03-14 Precision dentistry—what it is, where it fails (yet), and how to get there Schwendicke, Falk Krois, Joachim Clin Oral Investig Review OBJECTIVES: Dentistry is stuck between the one-size-fits-all approach towards diagnostics and therapy employed for a century and the era of stratified medicine. The present review presents the concept of precision dentistry, i.e., the next step beyond stratification into risk groups, and lays out where we stand, but also what challenges we have ahead for precision dentistry to come true. MATERIAL AND METHODS: Narrative literature review. RESULTS: Current approaches for enabling more precise diagnostics and therapies focus on stratification of individuals using clinical or social risk factors or indicators. Most research in dentistry does not focus on predictions — the key for precision dentistry — but on associations. We critically discuss why both approaches (focus on a limited number of risk factors or indicators and on associations) are insufficient and elaborate on what we think may allow to overcome the status quo. CONCLUSIONS: Leveraging more diverse and broad data stemming from routine or unusual sources via advanced data analytics and testing the resulting prediction models rigorously may allow further steps towards more precise oral and dental care. CLINICAL SIGNIFICANCE: Precision dentistry refers to tailoring diagnostics and therapy to an individual; it builds on modelling, prediction making and rigorous testing. Most studies in the dental domain focus on showing associations, and do not attempt to make any predictions. Moreover, the datasets used are narrow and usually collected purposively following a clinical reasoning. Opening routine data silos and involving uncommon data sources to harvest broad data and leverage them using advanced analytics could facilitate precision dentistry. Springer Berlin Heidelberg 2022-03-14 2022 /pmc/articles/PMC8918420/ /pubmed/35284954 http://dx.doi.org/10.1007/s00784-022-04420-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Schwendicke, Falk
Krois, Joachim
Precision dentistry—what it is, where it fails (yet), and how to get there
title Precision dentistry—what it is, where it fails (yet), and how to get there
title_full Precision dentistry—what it is, where it fails (yet), and how to get there
title_fullStr Precision dentistry—what it is, where it fails (yet), and how to get there
title_full_unstemmed Precision dentistry—what it is, where it fails (yet), and how to get there
title_short Precision dentistry—what it is, where it fails (yet), and how to get there
title_sort precision dentistry—what it is, where it fails (yet), and how to get there
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918420/
https://www.ncbi.nlm.nih.gov/pubmed/35284954
http://dx.doi.org/10.1007/s00784-022-04420-1
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