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Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report
Toxic Epidermal Necrolysis/Steven–Johnson Syndrome (TEN/SJS) is one of the most serious dermatological adverse reactions triggered mainly by drugs and less likely by infections. COVID‐19 disease is caused by Sever Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) with a wide range of clinical ma...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918465/ https://www.ncbi.nlm.nih.gov/pubmed/35310321 http://dx.doi.org/10.1002/ccr3.5565 |
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author | Jouhar, Lamia Yahya, Marva Elsiddiq, Sohair |
author_facet | Jouhar, Lamia Yahya, Marva Elsiddiq, Sohair |
author_sort | Jouhar, Lamia |
collection | PubMed |
description | Toxic Epidermal Necrolysis/Steven–Johnson Syndrome (TEN/SJS) is one of the most serious dermatological adverse reactions triggered mainly by drugs and less likely by infections. COVID‐19 disease is caused by Sever Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) with a wide range of clinical manifestations. Skin involvement is common in COVID‐19 patients including urticaria, purpura, and vasculitis. There were reported cases of TEN/SJS in adults with COVID‐19 infections and only two reported cases in pediatric patients. The causality relationship between COVID‐19 infection and TEN/SJS was not established in most cases due to history of drug usage that could be the trigger. In this study, we are reporting a case of previously healthy child apart from COVID‐19 infection who was admitted to the intensive care unit with TEN involving more than 30% of body surface area confirmed by skin biopsy. The child was treated with intravenous immunoglobulins, steroids, and cyclosporin with a very good outcome. |
format | Online Article Text |
id | pubmed-8918465 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89184652022-03-18 Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report Jouhar, Lamia Yahya, Marva Elsiddiq, Sohair Clin Case Rep Case Reports Toxic Epidermal Necrolysis/Steven–Johnson Syndrome (TEN/SJS) is one of the most serious dermatological adverse reactions triggered mainly by drugs and less likely by infections. COVID‐19 disease is caused by Sever Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) with a wide range of clinical manifestations. Skin involvement is common in COVID‐19 patients including urticaria, purpura, and vasculitis. There were reported cases of TEN/SJS in adults with COVID‐19 infections and only two reported cases in pediatric patients. The causality relationship between COVID‐19 infection and TEN/SJS was not established in most cases due to history of drug usage that could be the trigger. In this study, we are reporting a case of previously healthy child apart from COVID‐19 infection who was admitted to the intensive care unit with TEN involving more than 30% of body surface area confirmed by skin biopsy. The child was treated with intravenous immunoglobulins, steroids, and cyclosporin with a very good outcome. John Wiley and Sons Inc. 2022-03-13 /pmc/articles/PMC8918465/ /pubmed/35310321 http://dx.doi.org/10.1002/ccr3.5565 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Jouhar, Lamia Yahya, Marva Elsiddiq, Sohair Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report |
title | Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report |
title_full | Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report |
title_fullStr | Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report |
title_full_unstemmed | Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report |
title_short | Toxic Epidermal Necrolysis associated with COVID‐19 infection: A case report |
title_sort | toxic epidermal necrolysis associated with covid‐19 infection: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918465/ https://www.ncbi.nlm.nih.gov/pubmed/35310321 http://dx.doi.org/10.1002/ccr3.5565 |
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