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The Diagnostic Value of Pan-Trk Expression to Detect Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion in CNS Tumours: A Study Using Next-Generation Sequencing Platform

Background: Neurotrophic tyrosine receptor kinase (NTRK) fusion has been detected in rare types of CNS tumours, which can promote tumorigenesis. The efficacy of Trk inhibitor became a significant therapeutic interest. Our aim was to investigate whether Pan-Trk immunohistochemistry (IHC) is a reliabl...

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Detalles Bibliográficos
Autores principales:	Mohamed, Fawaz, Kurdi, Maher, Baeesa, Saleh, Sabbagh, Abdulrahman Jafar, Hakamy, Sahar, Maghrabi, Yazid, Alshedokhi, Mohammed, Dallol, Ashraf, Halawa, Taher F., Najjar, Ahmed A., Fdl-Elmula, Imad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pathology and Oncology Archive
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918486/ https://www.ncbi.nlm.nih.gov/pubmed/35295612 http://dx.doi.org/10.3389/pore.2022.1610233

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