A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia

Regulatory T cells (Tregs) are capable of inhibiting the proliferation, activation and function of T cells and play an important role in impeding the immune response to cancer. In chronic lymphocytic leukemia (CLL) a dysfunctional immune response and elevated percentage of effector-like phenotype Tr...

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Detalles Bibliográficos
Autores principales: Goral, Agnieszka, Firczuk, Malgorzata, Fidyt, Klaudyna, Sledz, Marta, Simoncello, Francesca, Siudakowska, Karolina, Pagano, Giulia, Moussay, Etienne, Paggetti, Jérôme, Nowakowska, Patrycja, Gobessi, Stefania, Barankiewicz, Joanna, Salomon-Perzynski, Aleksander, Benvenuti, Federica, Efremov, Dimitar G., Juszczynski, Przemyslaw, Lech-Maranda, Ewa, Muchowicz, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918500/
https://www.ncbi.nlm.nih.gov/pubmed/35296093
http://dx.doi.org/10.3389/fimmu.2022.781364

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