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The Outer Membrane Lipoprotein Tp0136 Stimulates Human Platelet Activation and Aggregation Through PAR1 to Enhance G(q)/G(i) Signaling
BACKGROUND: Chancre self-healing, a typical clinical phenomenon of primary syphilis, is essentially wound healing. The first response to a wound is constriction of the injured blood vessels and activation of platelets to form a fibrin clot. However, the role of Treponema pallidum in platelet activat...
Autores principales: | Xu, Qiu-Yan, Wang, Yong-Jing, Lin, Li-Rong, Liu, Li-Li, Yang, Tian-Ci |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918515/ https://www.ncbi.nlm.nih.gov/pubmed/35296084 http://dx.doi.org/10.3389/fimmu.2022.818151 |
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