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Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells

Chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) are malignancies characterized by the dependence on B-cell receptor (BCR) signaling and by the high expression of ROR1, the cell surface receptor for Wnt-5a. Both, BCR and ROR1 are therapeutic targets in these diseases and the underst...

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Detalles Bibliográficos
Autores principales:	Dave, Zankruti, Vondálová Blanářová, Olga, Čada, Štěpán, Janovská, Pavlína, Zezula, Nikodém, Běhal, Martin, Hanáková, Kateřina, Ganji, Sri Ranjani, Krejci, Pavel, Gömöryová, Kristína, Peschelová, Helena, Šmída, Michal, Zdráhal, Zbyněk, Pavlová, Šárka, Kotašková, Jana, Pospíšilová, Šárka, Bryja, Vítězslav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918536/ https://www.ncbi.nlm.nih.gov/pubmed/35295854 http://dx.doi.org/10.3389/fcell.2022.838871

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