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Dynamics of Serum Pregenome RNA in Chronic Hepatitis B Patients Receiving 96-Month Nucleos(t)ide Analog Therapy

BACKGROUND: Tissue covalently closed circular DNA (cccDNA) can reflect the activity of HBV replication. However, it is impractical to assess intrahepatic cccDNA in every outpatient. Serum pregenome RNA (pgRNA) is transcribed from intrahepatic cccDNA and may reflect the activity of intrahepatic cccDN...

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Detalles Bibliográficos
Autores principales: Tao, Yachao, Wang, Menglan, Liao, Juan, Cheng, Xing, He, Min, Zhang, Dongmei, Zhou, Taoyou, Chen, Jie, Chen, Enqiang, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918695/
https://www.ncbi.nlm.nih.gov/pubmed/35295596
http://dx.doi.org/10.3389/fmed.2022.787770