Targeted long-read sequencing reveals clonally expanded HBV-associated chromosomal translocations in patients with chronic hepatitis B

BACKGROUND & AIMS: HBV infects over 257 million people worldwide and is associated with the development of hepatocellular carcinoma (HCC). Integration of HBV DNA into the host genome is likely a key driver of HCC oncogenesis. Here, we utilise targeted long-read sequencing to determine the struct...

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Detalles Bibliográficos
Autores principales: van Buuren, Nicholas, Ramirez, Ricardo, Soulette, Cameron, Suri, Vithika, Han, Dong, May, Lindsey, Turner, Scott, Parvangada, P.C., Martin, Ross, Chan, Henry L.Y., Marcellin, Patrick, Buti, Maria, Bui, Nam, Bhardwaj, Neeru, Gaggar, Anuj, Li, Li, Mo, Hongmei, Feierbach, Becket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918852/
https://www.ncbi.nlm.nih.gov/pubmed/35295767
http://dx.doi.org/10.1016/j.jhepr.2022.100449

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