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Tubulin/microtubules as novel clozapine targets

AIM: Clozapine is currently the only effective drug for treatment‐resistant schizophrenia; nonetheless, its pharmacological mechanism remains unclear, and its administration is limited because of severe adverse effects. By comparing the binding proteins of clozapine and its derivative olanzapine, wh...

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Detalles Bibliográficos
Autores principales: Hino, Mizuki, Kondo, Takeshi, Kunii, Yasuto, Matsumoto, Junya, Wada, Akira, Niwa, Shin‐ichi, Setou, Mitsutoshi, Yabe, Hirooki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919115/
https://www.ncbi.nlm.nih.gov/pubmed/34964309
http://dx.doi.org/10.1002/npr2.12221