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Tubulin/microtubules as novel clozapine targets
AIM: Clozapine is currently the only effective drug for treatment‐resistant schizophrenia; nonetheless, its pharmacological mechanism remains unclear, and its administration is limited because of severe adverse effects. By comparing the binding proteins of clozapine and its derivative olanzapine, wh...
Autores principales: | Hino, Mizuki, Kondo, Takeshi, Kunii, Yasuto, Matsumoto, Junya, Wada, Akira, Niwa, Shin‐ichi, Setou, Mitsutoshi, Yabe, Hirooki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919115/ https://www.ncbi.nlm.nih.gov/pubmed/34964309 http://dx.doi.org/10.1002/npr2.12221 |
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