Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity

The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes for a weakening of the pandemic. We argue that the lower severity of Omicron is a coincidence and that ongoing rapid antigenic evolution is likely to produce new variants that may...

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Detalles Bibliográficos
Autores principales: Markov, Peter V., Katzourakis, Aris, Stilianakis, Nikolaos I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919145/
https://www.ncbi.nlm.nih.gov/pubmed/35288685
http://dx.doi.org/10.1038/s41579-022-00722-z
Descripción
Sumario:The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes for a weakening of the pandemic. We argue that the lower severity of Omicron is a coincidence and that ongoing rapid antigenic evolution is likely to produce new variants that may escape immunity and be more severe.

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