Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity

The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes for a weakening of the pandemic. We argue that the lower severity of Omicron is a coincidence and that ongoing rapid antigenic evolution is likely to produce new variants that may...

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Autores principales: Markov, Peter V., Katzourakis, Aris, Stilianakis, Nikolaos I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919145/
https://www.ncbi.nlm.nih.gov/pubmed/35288685
http://dx.doi.org/10.1038/s41579-022-00722-z
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author Markov, Peter V.
Katzourakis, Aris
Stilianakis, Nikolaos I.
author_facet Markov, Peter V.
Katzourakis, Aris
Stilianakis, Nikolaos I.
author_sort Markov, Peter V.
collection PubMed
description The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes for a weakening of the pandemic. We argue that the lower severity of Omicron is a coincidence and that ongoing rapid antigenic evolution is likely to produce new variants that may escape immunity and be more severe.
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spelling pubmed-89191452022-03-14 Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity Markov, Peter V. Katzourakis, Aris Stilianakis, Nikolaos I. Nat Rev Microbiol Comment The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes for a weakening of the pandemic. We argue that the lower severity of Omicron is a coincidence and that ongoing rapid antigenic evolution is likely to produce new variants that may escape immunity and be more severe. Nature Publishing Group UK 2022-03-14 2022 /pmc/articles/PMC8919145/ /pubmed/35288685 http://dx.doi.org/10.1038/s41579-022-00722-z Text en © Springer Nature Limited 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comment
Markov, Peter V.
Katzourakis, Aris
Stilianakis, Nikolaos I.
Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
title Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
title_full Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
title_fullStr Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
title_full_unstemmed Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
title_short Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity
title_sort antigenic evolution will lead to new sars-cov-2 variants with unpredictable severity
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919145/
https://www.ncbi.nlm.nih.gov/pubmed/35288685
http://dx.doi.org/10.1038/s41579-022-00722-z
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