HDLs extract lipophilic drugs from cells

High-density lipoproteins (HDLs) prevent cell death induced by a variety of cytotoxic drugs. The underlying mechanisms are however still poorly understood. Here, we present evidence that HDLs efficiently protect cells against thapsigargin (TG), a sarco/endoplasmic reticulum (ER) Ca(2+)-ATPase (SERCA...

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Detalles Bibliográficos
Autores principales: Zheng, Adi, Dubuis, Gilles, Georgieva, Maria, Mendes Ferreira, Carla Susana, Serulla, Marc, del Carmen Conde Rubio, Maria, Trofimenko, Evgeniya, Mercier, Thomas, Decosterd, Laurent, Widmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919334/
https://www.ncbi.nlm.nih.gov/pubmed/34981808
http://dx.doi.org/10.1242/jcs.258644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919334/
https://www.ncbi.nlm.nih.gov/pubmed/34981808
http://dx.doi.org/10.1242/jcs.258644

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