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MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer

BACKGROUND: Endogenous retroviruses (ERVs) are highly expressed in various cancer types and are associated with increased innate immune response and better efficacy of antiprogrammed death-1/ligand-1 (anti-PD1/PD-L1)-directed immune checkpoint inhibitors (ICI) in preclinical models. However, their r...

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Detalles Bibliográficos
Autores principales:	Lecuelle, Julie, Favier, Laure, Fraisse, Cléa, Lagrange, Aurélie, Kaderbhai, Coureche, Boidot, Romain, Chevrier, Sandy, Joubert, Philippe, Routy, Bertrand, Truntzer, Caroline, Ghiringhelli, Francois
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919440/ https://www.ncbi.nlm.nih.gov/pubmed/35277462 http://dx.doi.org/10.1136/jitc-2021-004241

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