Decreased CSF clearance and increased brain amyloid in Alzheimer’s disease

BACKGROUND: In sporadic Alzheimer’s disease (AD), brain amyloid-beta (Aβ) deposition is believed to be a consequence of impaired Aβ clearance, but this relationship is not well established in living humans. CSF clearance, a major feature of brain glymphatic clearance (BGC), has been shown to be abno...

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Detalles Bibliográficos
Autores principales: Li, Yi, Rusinek, Henry, Butler, Tracy, Glodzik, Lidia, Pirraglia, Elizabeth, Babich, John, Mozley, P. David, Nehmeh, Sadek, Pahlajani, Silky, Wang, Xiuyuan, Tanzi, Emily B., Zhou, Liangdong, Strauss, Sara, Carare, Roxana O., Theise, Neil, Okamura, Nobuyuki, de Leon, Mony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919541/
https://www.ncbi.nlm.nih.gov/pubmed/35287702
http://dx.doi.org/10.1186/s12987-022-00318-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919541/
https://www.ncbi.nlm.nih.gov/pubmed/35287702
http://dx.doi.org/10.1186/s12987-022-00318-y

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