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Decreased CSF clearance and increased brain amyloid in Alzheimer’s disease
BACKGROUND: In sporadic Alzheimer’s disease (AD), brain amyloid-beta (Aβ) deposition is believed to be a consequence of impaired Aβ clearance, but this relationship is not well established in living humans. CSF clearance, a major feature of brain glymphatic clearance (BGC), has been shown to be abno...
Autores principales: | Li, Yi, Rusinek, Henry, Butler, Tracy, Glodzik, Lidia, Pirraglia, Elizabeth, Babich, John, Mozley, P. David, Nehmeh, Sadek, Pahlajani, Silky, Wang, Xiuyuan, Tanzi, Emily B., Zhou, Liangdong, Strauss, Sara, Carare, Roxana O., Theise, Neil, Okamura, Nobuyuki, de Leon, Mony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919541/ https://www.ncbi.nlm.nih.gov/pubmed/35287702 http://dx.doi.org/10.1186/s12987-022-00318-y |
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