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EnsembleFam: towards more accurate protein family prediction in the twilight zone
BACKGROUND: Current protein family modeling methods like profile Hidden Markov Model (pHMM), k-mer based methods, and deep learning-based methods do not provide very accurate protein function prediction for proteins in the twilight zone, due to low sequence similarity to reference proteins with know...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919565/ https://www.ncbi.nlm.nih.gov/pubmed/35287576 http://dx.doi.org/10.1186/s12859-022-04626-w |