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Parsimonious Clone Tree Integration in cancer
BACKGROUND: Every tumor is composed of heterogeneous clones, each corresponding to a distinct subpopulation of cells that accumulated different types of somatic mutations, ranging from single-nucleotide variants (SNVs) to copy-number aberrations (CNAs). As the analysis of this intra-tumor heterogene...
Autores principales: | Sashittal, Palash, Zaccaria, Simone, El-Kebir, Mohammed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919608/ https://www.ncbi.nlm.nih.gov/pubmed/35282838 http://dx.doi.org/10.1186/s13015-022-00209-9 |
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