OPAL: a randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain—a statistical analysis plan

BACKGROUND: Low back and neck pain are a leading cause of disease burden globally. Opioids are recommended in guidelines for acute low back and neck pain; however, there is a lack of compelling efficacy data to support this. METHODS: The OPAL trial is a prospectively registered, triple-blinded, rand...

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Detalles Bibliográficos
Autores principales: Jones, Caitlin MP, Lin, Chung-Wei Christine, Day, Richard O., Koes, Bart W., Latimer, Jane, Maher, Chris G., McLachlan, Andrew, Billot, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919636/
https://www.ncbi.nlm.nih.gov/pubmed/35287698
http://dx.doi.org/10.1186/s13063-022-06028-y

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