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Rv3737 is required for Mycobacterium tuberculosis growth in vitro and in vivo and correlates with bacterial load and disease severity in human tuberculosis

BACKGROUND: Rv3737 is the sole homologue of multifunctional transporter ThrE in Mycobacterium tuberculosis (Mtb). In this study, we aimed to investigate whether this transporter participates in vitro and in vivo survival of Mtb. METHODS: To characterize the role of Rv3737, we constructed and charact...

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Detalles Bibliográficos
Autores principales:	Li, Qing, Peng, Zhangli, Fu, Xuefeng, Wang, Hong, Zhao, Zhaoliang, Pang, Yu, Chen, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919692/ https://www.ncbi.nlm.nih.gov/pubmed/35287590 http://dx.doi.org/10.1186/s12879-021-06967-y

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