Cargando…

Rv3737 is required for Mycobacterium tuberculosis growth in vitro and in vivo and correlates with bacterial load and disease severity in human tuberculosis

BACKGROUND: Rv3737 is the sole homologue of multifunctional transporter ThrE in Mycobacterium tuberculosis (Mtb). In this study, we aimed to investigate whether this transporter participates in vitro and in vivo survival of Mtb. METHODS: To characterize the role of Rv3737, we constructed and charact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qing, Peng, Zhangli, Fu, Xuefeng, Wang, Hong, Zhao, Zhaoliang, Pang, Yu, Chen, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919692/ https://www.ncbi.nlm.nih.gov/pubmed/35287590 http://dx.doi.org/10.1186/s12879-021-06967-y

Ejemplares similares

Evaluation of Rv0220, Rv2958c, Rv2994 and Rv3347c of Mycobacterium tuberculosis for serodiagnosis of tuberculosis
por: You, Xiaolong, et al.
Publicado: (2017)

Investigating Mycobacterium tuberculosis sufR (rv1460) in vitro and ex vivo expression and immunogenicity
por: Baatjies, Lucinda, et al.
Publicado: (2023)

In vitro modeling of isoniazid resistance mechanisms in Mycobacterium tuberculosis H37Rv
por: Dokrungkoon, Thanadon, et al.
Publicado: (2023)

Rv1453 is associated with clofazimine resistance in Mycobacterium tuberculosis
por: Zhang, Lei, et al.
Publicado: (2023)

Characterization of Rv0888, a Novel Extracellular Nuclease from Mycobacterium tuberculosis
por: Dang, Guanghui, et al.
Publicado: (2016)

Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis
por: Peterson, Eliza J.R., et al.
Publicado: (2016)

Rv2031c of Mycobacterium tuberculosis: a master regulator of Rv2028–Rv2031 (HspX) operon
por: Mushtaq, Khurram, et al.
Publicado: (2015)

Characterization of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
por: Guo, Jiubiao, et al.
Publicado: (2010)

Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis
por: Zhao, Nan, et al.
Publicado: (2015)

Mycobacterium tuberculosis Rv0494 Protein Contributes to Mycobacterial Persistence
por: Ji, Lei, et al.
Publicado: (2023)

Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection
por: Kimuda, Simon G., et al.
Publicado: (2017)

Transcription factors Rv0081 and Rv3334 connect the early and the enduring hypoxic response of Mycobacterium tuberculosis
por: Sun, Xian, et al.
Publicado: (2018)

Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis
por: Zheng, Xiangdong, et al.
Publicado: (2011)

PGRS Domain of Rv0297 of Mycobacterium tuberculosis Is Involved in Modulation of Macrophage Functions to Favor Bacterial Persistence
por: Sharma, Tarina, et al.
Publicado: (2020)

A putative short-chain dehydrogenase Rv0148 of Mycobacterium tuberculosis affects bacterial survival and virulence
por: Bhargavi, Gunapati, et al.
Publicado: (2022)

Structural and functional analysis of the transcriptional regulator Rv3066 of Mycobacterium tuberculosis
por: Bolla, Jani Reddy, et al.
Publicado: (2012)

Correction: Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis
Publicado: (2015)

Circularization of rv0678 for Genotypic Bedaquiline Resistance Testing of Mycobacterium tuberculosis
por: Limberis, Jason D., et al.
Publicado: (2023)

Triclosan-induced genes Rv1686c-Rv1687c and Rv3161c are not involved in triclosan resistance in Mycobacterium tuberculosis
por: Gomez, Andromeda, et al.
Publicado: (2016)

Enhanced serodiagnostic potential of a fusion molecule consisting of Rv1793, Rv2628 and a truncated Rv2608 of Mycobacterium tuberculosis
por: Sulman, Sadaf, et al.
Publicado: (2021)

Mycobacterium tuberculosis Rv0341 Promotes Mycobacterium Survival in In Vitro Hostile Environments and within Macrophages and Induces Cytokines Expression
por: Abdalla, Abualgasim Elgaili, et al.
Publicado: (2020)

Secreted Mycobacterium tuberculosis Rv3654c and Rv3655c Proteins Participate in the Suppression of Macrophage Apoptosis
por: Danelishvili, Lia, et al.
Publicado: (2010)

Antigens Rv0310c and Rv1255c are promising novel biomarkers for the diagnosis of Mycobacterium tuberculosis infection
por: Luo, Liulin, et al.
Publicado: (2017)

MiaA (Rv2727c) mediated tRNA isopentenylation of Mycobacterium tuberculosis H37Rv
por: Soman, Smitha, et al.
Publicado: (2022)

Rv2190c, an NlpC/P60 Family Protein, Is Required for Full Virulence of Mycobacterium tuberculosis
por: Parthasarathy, Geetha, et al.
Publicado: (2012)

glpx Gene in Mycobacterium tuberculosis Is Required for In Vitro Gluconeogenic Growth and In Vivo Survival
por: Gutka, Hiten J., et al.
Publicado: (2015)

Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates
por: Shahi, Fatemeh, et al.
Publicado: (2021)

Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv)
por: Singla, Deepak, et al.
Publicado: (2013)

The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis
por: Kumar, Atul, et al.
Publicado: (2013)

Mycobacterium tuberculosis H37Rv infection regulates alternative splicing in Macrophages
por: Zhang, Wei, et al.
Publicado: (2018)

Expression and production of soluble Mycobacterium tuberculosis H37Rv mycosin-3
por: Fang, Zhuo, et al.
Publicado: (2016)

Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis
por: Lee, Sanghyun, et al.
Publicado: (2019)

Mycobacterium tuberculosis Rv0991c Is a Redox-Regulated Molecular Chaperone
por: Becker, Samuel H., et al.
Publicado: (2020)

Mycobacterium tuberculosis Rv0309 Dampens the Inflammatory Response and Enhances Mycobacterial Survival
por: Peng, Yongchong, et al.
Publicado: (2022)

Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis
por: Shelton, Catherine D., et al.
Publicado: (2021)

Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis
por: Black, Katherine A., et al.
Publicado: (2021)

Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv
por: Asai, Masanori, et al.
Publicado: (2022)

A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome
por: Chitale, Poonam, et al.
Publicado: (2022)

Molecular modeling, simulation and docking of Rv1250 protein from Mycobacterium tuberculosis
por: Choudhary, Sumita, et al.
Publicado: (2023)

The Rv3799–Rv3807 gene cluster in Mycobacterium tuberculosis genome corresponds to the ‘Ancient Conserved Region’ in CMN mycolyltransferases
por: Ramulu, Hemalatha G., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_3clf0sr60cbhjncuge5271otr7