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Novel T cell interferon gamma release assay (IGRA) using spike recombinant protein for COVID19 vaccine response and Nucleocapsid for SARS-Cov2 response

We explored the performance of a whole blood interferon gamma release assay (IGRA) based on the stimulation of SARS-Cov2-specific T cells by purified recombinant proteins. Twenty volunteers vaccinated with BNT162b2 were selected first for T cell response evaluation using an in-house IGRA, a commerci...

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Detalles Bibliográficos
Autores principales: Renaudineau, Yves, Abravanel, Florence, Izopet, Jacques, Bost, Chloé, Treiner, Emmanuel, Congy, Nicolas, Blancher, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920083/
https://www.ncbi.nlm.nih.gov/pubmed/35301104
http://dx.doi.org/10.1016/j.clim.2022.108979