Cargando…

A systems radiation biology approach to unravel the role of chronic low-dose-rate gamma-irradiation in inducing premature senescence in endothelial cells

PURPOSE: The aim of this study was to explore the effects of chronic low-dose-rate gamma-radiation at a multi-scale level. The specific objective was to obtain an overall view of the endothelial cell response, by integrating previously published data on different cellular endpoints and highlighting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Babini, Gabriele, Baiocco, Giorgio, Barbieri, Sofia, Morini, Jacopo, Sangsuwan, Traimate, Haghdoost, Siamak, Yentrapalli, Ramesh, Azimzadeh, Omid, Rombouts, Charlotte, Aerts, An, Quintens, Roel, Ebrahimian, Teni, Benotmane, Mohammed Abderrafi, Ramadan, Raghda, Baatout, Sarah, Tapio, Soile, Harms-Ringdahl, Mats, Ottolenghi, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920222/ https://www.ncbi.nlm.nih.gov/pubmed/35286349 http://dx.doi.org/10.1371/journal.pone.0265281

Ejemplares similares

The PI3K/Akt/mTOR Pathway Is Implicated in the Premature Senescence of Primary Human Endothelial Cells Exposed to Chronic Radiation
por: Yentrapalli, Ramesh, et al.
Publicado: (2013)

Cardiovascular diseases related to ionizing radiation: The risk of low-dose exposure (Review)
por: Baselet, Bjorn, et al.
Publicado: (2016)

Meta-Analysis of RNA-Seq Datasets Identifies Novel Players in Glioblastoma
por: Sallam, Magy, et al.
Publicado: (2022)

The Interplay between Radioresistant Caco-2 Cells and the Immune System Increases Epithelial Layer Permeability and Alters Signaling Protein Spectrum
por: Morini, Jacopo, et al.
Publicado: (2017)

Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
por: Drobin, Kimi, et al.
Publicado: (2020)

Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?
por: Sallam, Magy, et al.
Publicado: (2021)

DNA Methylation Alterations in Fractionally Irradiated Rats and Breast Cancer Patients Receiving Radiotherapy
por: Sallam, Magy, et al.
Publicado: (2022)

Brain Radiation Information Data Exchange (BRIDE): integration of experimental data from low-dose ionising radiation research for pathway discovery
por: Karapiperis, Christos, et al.
Publicado: (2016)

In vitro γ-ray-induced inflammatory response is dominated by culturing conditions rather than radiation exposures
por: Babini, G., et al.
Publicado: (2015)

WHAT ROLES FOR TRACK-STRUCTURE AND MICRODOSIMETRY IN THE ERA OF -omics AND SYSTEMS BIOLOGY?
por: Baiocco, G, et al.
Publicado: (2019)

Tomato juice intake suppressed serum concentration of 8-oxodG after extensive physical activity
por: Harms-Ringdahl, Mats, et al.
Publicado: (2012)

Combined Exposure to Simulated Microgravity and Acute or Chronic Radiation Reduces Neuronal Network Integrity and Survival
por: Pani, Giuseppe, et al.
Publicado: (2016)

Morphological and Physiological Changes in Mature In Vitro Neuronal Networks towards Exposure to Short-, Middle- or Long-Term Simulated Microgravity
por: Pani, Giuseppe, et al.
Publicado: (2013)

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses
por: Baselet, Bjorn, et al.
Publicado: (2017)

The role of connexin proteins and their channels in radiation-induced atherosclerosis
por: Ramadan, Raghda, et al.
Publicado: (2021)

Correction to: The role of connexin proteins and their channels in radiation-induced atherosclerosis
por: Ramadan, Raghda, et al.
Publicado: (2021)

A Co-culture Method to Investigate the Crosstalk Between X-ray Irradiated Caco-2 Cells and PBMC
por: Babini, Gabriele, et al.
Publicado: (2018)

Predicting DNA damage foci and their experimental readout with 2D microscopy: a unified approach applied to photon and neutron exposures
por: Barbieri, Sofia, et al.
Publicado: (2019)

The origin of neutron biological effectiveness as a function of energy
por: Baiocco, G., et al.
Publicado: (2016)

Current Evidence for Developmental, Structural, and Functional Brain Defects following Prenatal Radiation Exposure
por: Verreet, Tine, et al.
Publicado: (2016)

Tolerance to Gamma Radiation in the Tardigrade Hypsibius dujardini from Embryo to Adult Correlate Inversely with Cellular Proliferation
por: Beltrán-Pardo, Eliana, et al.
Publicado: (2015)

Chronic Low Dose Rate Ionizing Radiation Exposure Induces Premature Senescence in Human Fibroblasts that Correlates with Up Regulation of Proteins Involved in Protection against Oxidative Stress
por: Loseva, Olga, et al.
Publicado: (2014)

Non-conventional apoptotic response to ionising radiation mediated by N-methyl D-aspartate receptors in immature neuronal cells
por: SAMARI, NADA, et al.
Publicado: (2013)

miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease
por: Eken, Suzanne M., et al.
Publicado: (2019)

X-irradiation induces acute and early term inflammatory responses in atherosclerosis-prone ApoE(−)/(−) mice and in endothelial cells
por: Ramadan, Raghda, et al.
Publicado: (2021)

Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose
por: Baselet, Bjorn, et al.
Publicado: (2017)

Transcriptomic and proteomic analysis of mouse radiation-induced acute myeloid leukaemia (AML)
por: Badie, Christophe, et al.
Publicado: (2016)

In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome
por: Bakshi, Mayur V., et al.
Publicado: (2016)

Multidisciplinary European Low Dose Initiative (MELODI): strategic research agenda for low dose radiation risk research
por: Kreuzer, M., et al.
Publicado: (2017)

Exposure to Ionizing Radiation Triggers Prolonged Changes in Circular RNA Abundance in the Embryonic Mouse Brain and Primary Neurons
por: Mbouombouo Mfossa, André Claude, et al.
Publicado: (2019)

Effects of Ionizing Radiation on Embryos of the Tardigrade Milnesium cf. tardigradum at Different Stages of Development
por: Beltrán-Pardo, Eliana, et al.
Publicado: (2013)

Single and fractionated ionizing radiation induce alterations in endothelial connexin expression and channel function
por: Ramadan, Raghda, et al.
Publicado: (2019)

Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage
por: Ramadan, Raghda, et al.
Publicado: (2020)

Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry
por: Macaeva, Ellina, et al.
Publicado: (2016)

Exposure to Low to Moderate Doses of Ionizing Radiation Induces A Reduction of Pro-Inflammatory Ly6chigh Monocytes and a U-Curved Response of T Cells in APOE -/- Mice
por: Rey, N., et al.
Publicado: (2021)

Radiation-induced cell cycle perturbations: a computational tool validated with flow-cytometry data
por: Lonati, Leonardo, et al.
Publicado: (2021)

A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis
por: Verreet, Tine, et al.
Publicado: (2015)

A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project
por: Andreassi, Maria Grazia, et al.
Publicado: (2023)

Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development
por: Quintens, Roel, et al.
Publicado: (2015)

Folic Acid Fortification Prevents Morphological and Behavioral Consequences of X-Ray Exposure During Neurulation
por: Craenen, Kai, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9gccefufr6a2mbb9g4bmes0ota