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Metronidazole treatment rapidly reduces genital inflammation through effects on bacterial vaginosis–associated bacteria rather than lactobacilli

BACKGROUND: Bacterial vaginosis (BV) causes genital inflammation and increases HIV risk, whereas a vaginal microbiota dominated by Lactobacillus species is associated with immune quiescence and relative HIV protection. BV treatment reduces genital inflammation, but it is unclear whether this reducti...

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Detalles Bibliográficos
Autores principales: Armstrong, Eric, Hemmerling, Anke, Miller, Steve, Burke, Kerianne E., Newmann, Sara J., Morris, Sheldon R., Reno, Hilary, Huibner, Sanja, Kulikova, Maria, Liu, Rachel, Crawford, Emily D., Castañeda, Gloria R., Nagelkerke, Nico, Coburn, Bryan, Cohen, Craig R., Kaul, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920324/
https://www.ncbi.nlm.nih.gov/pubmed/35113809
http://dx.doi.org/10.1172/JCI152930