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ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance

Glioblastoma (GBM) is the most common and lethal primary malignant brain tumor, containing GBM stem cells (GSCs) that contribute to therapeutic resistance and relapse. Exposing potential GSC vulnerabilities may provide therapeutic strategies against GBM. Here, we interrogated the role of adenosine-t...

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Detalles Bibliográficos
Autores principales:	Jiang, Li, Hao, Yajing, Shao, Changwei, Wu, Qiulian, Prager, Briana C., Gimple, Ryan C., Sulli, Gabriele, Kim, Leo J.Y., Zhang, Guoxin, Qiu, Zhixin, Zhu, Zhe, Fu, Xiang-Dong, Rich, Jeremy N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920333/ https://www.ncbi.nlm.nih.gov/pubmed/35133980 http://dx.doi.org/10.1172/JCI143397

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