Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation

The causative role of inflammation in hypertension-related cardiovascular diseases is evident and calls for development of specific immunomodulatory therapies. We tested the therapeutic efficacy and mechanisms of action of developmental endothelial locus-1 (DEL-1), an endogenous antiinflammatory fac...

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Detalles Bibliográficos
Autores principales: Failer, Theresa, Amponsah-Offeh, Michael, Neuwirth, Aleš, Kourtzelis, Ioannis, Subramanian, Pallavi, Mirtschink, Peter, Peitzsch, Mirko, Matschke, Klaus, Tugtekin, Sems M., Kajikawa, Tetsuhiro, Li, Xiaofei, Steglich, Anne, Gembardt, Florian, Wegner, Annika C., Hugo, Christian, Hajishengallis, George, Chavakis, Triantafyllos, Deussen, Andreas, Todorov, Vladimir, Kopaliani, Irakli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920341/
https://www.ncbi.nlm.nih.gov/pubmed/35133978
http://dx.doi.org/10.1172/JCI126155

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