Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia

Age‐related muscle atrophy and weakness, or sarcopenia, are significant contributors to compromised health and quality of life in the elderly. While the mechanisms driving this pathology are not fully defined, reactive oxygen species, neuromuscular junction (NMJ) disruption, and loss of innervation...

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Detalles Bibliográficos
Autores principales: Ahn, Bumsoo, Ranjit, Rojina, Kneis, Parker, Xu, Hongyang, Piekarz, Katarzyna M., Freeman, Willard M., Kinter, Michael, Richardson, Arlan, Ran, Qitao, Brooks, Susan V., Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920438/
https://www.ncbi.nlm.nih.gov/pubmed/35199907
http://dx.doi.org/10.1111/acel.13569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920438/
https://www.ncbi.nlm.nih.gov/pubmed/35199907
http://dx.doi.org/10.1111/acel.13569

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