ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first‐degree relatives of type 2 diabetics

Senescence of adipose precursor cells (APC) impairs adipogenesis, contributes to the age‐related subcutaneous adipose tissue (SAT) dysfunction, and increases risk of type 2 diabetes (T2D). First‐degree relatives of T2D individuals (FDR) feature restricted adipogenesis, reflecting the detrimental eff...

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Detalles Bibliográficos
Autores principales: Spinelli, Rosa, Florese, Pasqualina, Parrillo, Luca, Zatterale, Federica, Longo, Michele, D’Esposito, Vittoria, Desiderio, Antonella, Nerstedt, Annika, Gustafson, Birgit, Formisano, Pietro, Miele, Claudia, Raciti, Gregory Alexander, Napoli, Raffaele, Smith, Ulf, Beguinot, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920444/
https://www.ncbi.nlm.nih.gov/pubmed/35146866
http://dx.doi.org/10.1111/acel.13557

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