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Coding of chromatic spatial contrast by macaque V1 neurons

Color perception relies on comparisons between adjacent lights, but how the brain performs these comparisons is poorly understood. To elucidate the underlying mechanisms, we recorded spiking responses of individual V1 neurons in macaque monkeys to pairs of stimuli within the classical receptive fiel...

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Detalles Bibliográficos
Autores principales: De, Abhishek, Horwitz, Gregory D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920507/
https://www.ncbi.nlm.nih.gov/pubmed/35147497
http://dx.doi.org/10.7554/eLife.68133
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author De, Abhishek
Horwitz, Gregory D
author_facet De, Abhishek
Horwitz, Gregory D
author_sort De, Abhishek
collection PubMed
description Color perception relies on comparisons between adjacent lights, but how the brain performs these comparisons is poorly understood. To elucidate the underlying mechanisms, we recorded spiking responses of individual V1 neurons in macaque monkeys to pairs of stimuli within the classical receptive field (RF). We estimated the spatial-chromatic RF of each neuron and then presented customized colored edges using a closed-loop technique. We found that many double-opponent (DO) cells, which have spatially and chromatically opponent RFs, responded to chromatic contrast as a weighted sum, akin to how other V1 neurons responded to luminance contrast. Yet other neurons integrated chromatic signals nonlinearly, confirming that linear signal integration is not an obligate property of V1 neurons. The functional similarity of cone-opponent DO cells and cone non-opponent simple cells suggests that these two groups may share a common underlying circuitry, promotes the construction of image-computable models for full-color image representation, and sheds new light on V1 complex cells.
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spelling pubmed-89205072022-03-15 Coding of chromatic spatial contrast by macaque V1 neurons De, Abhishek Horwitz, Gregory D eLife Neuroscience Color perception relies on comparisons between adjacent lights, but how the brain performs these comparisons is poorly understood. To elucidate the underlying mechanisms, we recorded spiking responses of individual V1 neurons in macaque monkeys to pairs of stimuli within the classical receptive field (RF). We estimated the spatial-chromatic RF of each neuron and then presented customized colored edges using a closed-loop technique. We found that many double-opponent (DO) cells, which have spatially and chromatically opponent RFs, responded to chromatic contrast as a weighted sum, akin to how other V1 neurons responded to luminance contrast. Yet other neurons integrated chromatic signals nonlinearly, confirming that linear signal integration is not an obligate property of V1 neurons. The functional similarity of cone-opponent DO cells and cone non-opponent simple cells suggests that these two groups may share a common underlying circuitry, promotes the construction of image-computable models for full-color image representation, and sheds new light on V1 complex cells. eLife Sciences Publications, Ltd 2022-02-11 /pmc/articles/PMC8920507/ /pubmed/35147497 http://dx.doi.org/10.7554/eLife.68133 Text en © 2022, De and Horwitz https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
De, Abhishek
Horwitz, Gregory D
Coding of chromatic spatial contrast by macaque V1 neurons
title Coding of chromatic spatial contrast by macaque V1 neurons
title_full Coding of chromatic spatial contrast by macaque V1 neurons
title_fullStr Coding of chromatic spatial contrast by macaque V1 neurons
title_full_unstemmed Coding of chromatic spatial contrast by macaque V1 neurons
title_short Coding of chromatic spatial contrast by macaque V1 neurons
title_sort coding of chromatic spatial contrast by macaque v1 neurons
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920507/
https://www.ncbi.nlm.nih.gov/pubmed/35147497
http://dx.doi.org/10.7554/eLife.68133
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AT horwitzgregoryd codingofchromaticspatialcontrastbymacaquev1neurons