Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay

This study compared canine and feline fibroblast growth factor (FGF)-23 concentration measurements between automated chemiluminescence assay (CLEIA) and enzyme-linked immunosorbent assay (ELISA). Seventy serum samples each from dogs and cats were evaluated. FGF-23 measurements by CLEIA significantly...

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Autores principales: MIYAKAWA, Hirosumi, HSU, Huai-Hsun, OGAWA, Mizuki, MIYAGAWA, Yuichi, TAKEMURA, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920724/
https://www.ncbi.nlm.nih.gov/pubmed/34980757
http://dx.doi.org/10.1292/jvms.21-0566
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author MIYAKAWA, Hirosumi
HSU, Huai-Hsun
OGAWA, Mizuki
MIYAGAWA, Yuichi
TAKEMURA, Naoyuki
author_facet MIYAKAWA, Hirosumi
HSU, Huai-Hsun
OGAWA, Mizuki
MIYAGAWA, Yuichi
TAKEMURA, Naoyuki
author_sort MIYAKAWA, Hirosumi
collection PubMed
description This study compared canine and feline fibroblast growth factor (FGF)-23 concentration measurements between automated chemiluminescence assay (CLEIA) and enzyme-linked immunosorbent assay (ELISA). Seventy serum samples each from dogs and cats were evaluated. FGF-23 measurements by CLEIA significantly correlated with those of ELISA in both dogs and cats. The Bland–Altman test showed that FGF-23 between CLEIA and ELISA had fixed and proportional biases, respectively, in both dogs and cats. Measurements by CLEIA were lower than those of ELISA, especially in higher serum FGF-23 concentrations. This study showed that FGF-23 concentrations in dogs and cats can be evaluated by automated CLEIA. However, FGF-23 cannot be directly compared between CLEIA and ELISA.
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spelling pubmed-89207242022-03-25 Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay MIYAKAWA, Hirosumi HSU, Huai-Hsun OGAWA, Mizuki MIYAGAWA, Yuichi TAKEMURA, Naoyuki J Vet Med Sci Internal Medicine This study compared canine and feline fibroblast growth factor (FGF)-23 concentration measurements between automated chemiluminescence assay (CLEIA) and enzyme-linked immunosorbent assay (ELISA). Seventy serum samples each from dogs and cats were evaluated. FGF-23 measurements by CLEIA significantly correlated with those of ELISA in both dogs and cats. The Bland–Altman test showed that FGF-23 between CLEIA and ELISA had fixed and proportional biases, respectively, in both dogs and cats. Measurements by CLEIA were lower than those of ELISA, especially in higher serum FGF-23 concentrations. This study showed that FGF-23 concentrations in dogs and cats can be evaluated by automated CLEIA. However, FGF-23 cannot be directly compared between CLEIA and ELISA. The Japanese Society of Veterinary Science 2021-12-30 2022-02 /pmc/articles/PMC8920724/ /pubmed/34980757 http://dx.doi.org/10.1292/jvms.21-0566 Text en ©2022 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
MIYAKAWA, Hirosumi
HSU, Huai-Hsun
OGAWA, Mizuki
MIYAGAWA, Yuichi
TAKEMURA, Naoyuki
Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
title Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
title_full Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
title_fullStr Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
title_full_unstemmed Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
title_short Assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
title_sort assessment of the measurement of canine and feline serum fibroblast growth factor-23 concentrations by automated chemiluminescence immunoassay
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920724/
https://www.ncbi.nlm.nih.gov/pubmed/34980757
http://dx.doi.org/10.1292/jvms.21-0566
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