Viral load is associated with mitochondrial dysfunction and altered monocyte phenotype in acute severe SARS-CoV-2 infection

Monocytes play a major role in the initial innate immune response to SARS-CoV-2. Although viral load may correlate with several clinical outcomes in COVID-19, much less is known regarding their impact on innate immune phenotype. We evaluated the monocyte phenotype and mitochondrial function in sever...

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Detalles Bibliográficos
Autores principales: Romão, Pedro RT, Teixeira, Paula C, Schipper, Lucas, da Silva, Igor, Santana Filho, Paulo, Júnior, Luiz Carlos Rodrigues, Peres, Alessandra, Gonçalves da Fonseca, Simone, Chagas Monteiro, Marta, Lira, Fabio S, Andrey Cipriani Frade, Marco, Comerlato, Juliana, Comerlato, Carolina, Sant'Anna, Fernando Hayashi, Bessel, Marina, Abreu, Celina Monteiro, Wendland, Eliana M, Dorneles, Gilson P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920784/
https://www.ncbi.nlm.nih.gov/pubmed/35405594
http://dx.doi.org/10.1016/j.intimp.2022.108697

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