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Insignificant effects of loss of heterozygosity in HLA in the efficacy of immune checkpoint blockade treatment
BACKGROUND: It is assumed that loss of heterozygosity and allelic copy loss in HLA gene is associated with poor response rates in immune checkpoint inhibitor treatment. H-owever, the accurate extents or consistency in cancer types have not been explored. OBJECTIVE: The goal of this study is to inves...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921140/ https://www.ncbi.nlm.nih.gov/pubmed/35107815 http://dx.doi.org/10.1007/s13258-021-01207-8 |