Chronic isoprenaline/phenylephrine vs. exclusive isoprenaline stimulation in mice: critical contribution of alpha(1)-adrenoceptors to early cardiac stress responses

Hyperactivity of the sympathetic nervous system is a major driver of cardiac remodeling, exerting its effects through both α-, and β-adrenoceptors (α-, β-ARs). As the relative contribution of subtype α(1)-AR to cardiac stress responses remains poorly investigated, we subjected mice to either subcuta...

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Detalles Bibliográficos
Autores principales: Dewenter, Matthias, Pan, Jianyuan, Knödler, Laura, Tzschöckel, Niklas, Henrich, Julian, Cordero, Julio, Dobreva, Gergana, Lutz, Susanne, Backs, Johannes, Wieland, Thomas, Vettel, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921177/
https://www.ncbi.nlm.nih.gov/pubmed/35286475
http://dx.doi.org/10.1007/s00395-022-00920-z

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